Myasthenia gravis with thymoma and coexistent central hypothyroidism.
نویسندگان
چکیده
Myasthenia gravis (MG) is a well-known acquired autoimmune neuromuscular disorder. Patients with MG have a higher incidence of autoimmune disease than the normal population. MG is frequently associated with autoimmune thyroid disease, the most common of which is thyrotoxicosis. Associated hypothyroidism is not common, and the central (pituitary) origin, to our knowledge, has not yet been reported. We report an MG patient with thymoma that coexisted with central hypothyroidism, the correction of which is mandatory and significant to achieve remission.
منابع مشابه
Myasthenia gravis and pure red cell aplasia: a rare association.
This is a case of a patient who presented with generalised weakness, dysphagia and ptosis. Upon evaluating the patient, she was found to have myasthenia gravis (MG) with anaemia and hypothyroidism. Further evaluation for the cause of anaemia revealed that the patient had pure red cell aplasia (PRCA). CT thorax revealed a thymoma. The patient was given packed cell transfusions, steroids and pyri...
متن کاملMetaplastic thymoma with myasthenia gravis presumably caused by an accumulation of intratumoral immature T cells: a case report.
Among human neoplasms, thymomas are well known for their association with paraneoplastic autoimmune diseases such as myasthenia gravis. However, regarding rare metaplastic thymoma, only one case of an association with myasthenia gravis has been reported. Here, we present the second case of a 44-year-old woman with metaplastic thymoma associated with myasthenia gravis. In metaplastic thymoma, in...
متن کاملMyasthenia gravis associated with invasive malignant thymoma: two case reports and a review of the literature
INTRODUCTION Approximately ten to fifteen percent of patients with myasthenia gravis are found to have a thymoma, and twenty to twenty-five percent of patients with thymoma have myasthenia gravis. Thymomatous myasthenia gravis tends to have a difficult clinical course and poor prognosis. CASE PRESENTATION We report two cases (one patient of Asian ethnicity and the other of Caucasian ethnicity...
متن کاملMultiple Thymoma with Myasthenia Gravis
The actual incidence of multiple thymoma is unknown and rarely reported because it remains controversial whether the cases represent a disease of multicentric origin or a disease resulting from intrathymic metastasis. In this case, a patient underwent total thymectomy for multiple thymoma with myasthenia gravis via bilateral video-assisted thoracic surgery. A well-encapsulated multinodular cyst...
متن کاملIncreased mast cell density and microvessel density in the thymus of patients with myasthenia gravis.
There were investigated 15 cases with normal thymus removed during cardiac surgery and nine cases with clinical signs of myasthenia gravis. Four patients with myasthenia gravis had thymoma (three invasive, one non-invasive). Specimens were fixed in buffer formalin, embedded in paraffin and slides were stained with Hematoxylin-Eosin and Alcian blue-Safranin. Additional slides were stained for fa...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Journal of the Chinese Medical Association : JCMA
دوره 72 2 شماره
صفحات -
تاریخ انتشار 2009